On a mission to save lives by repurposing drugs
Every Cure is a nonprofit initiative utilizing AI to unlock the full potential of existing medicines to treat every disease and every patient they possibly can.
Photo Credit: Hannah Yoon
Thousands
Lives Saved
Our Story
Inspired by my personal journey discovering that a drug could be repurposed to save my life during medical school, I have been on a mission to find as many life-saving uses for existing medicines as possible. During this time, my colleagues and I at the University of Pennsylvania, CDCN, and Every Cure have advanced 14 repurposed drugs for multiple diseases, saving thousands of lives
The Problem
Today, more than 75% of the 18.5K recognized diseases do not have an FDA-approved treatment, affecting hundreds of millions of people. We know many of these diseases could be treated with many of the 4,000 FDA-approved drugs—at less than 1% the cost of developing a new drug.
But systemic barriers prevent this from happening. It’s just not profitable to pursue a new use for an existing drug, especially for rare diseases and the 80% of drugs that are already generic and inexpensive.
Our Work
We are pioneering a new approach called computational pharmacophenomics to interrogate the world’s biomedical knowledge to find and advance the most promising opportunities across all drugs and all diseases. We turn traditional drug repurposing on its head: instead of starting with a specific drug or disease of focus, we make predictions looking across all 4k approved drugs and all 18k recognized diseases to identify the highest potential opportunities. This means that every single disease is in our platform and we are constantly evaluating all opportunities to find the very best ones to advance to patients.
Our Mission
Dr. David Fajgenbaum has dedicated his life to unlocking the full potential of medicine—not just for one disease, but for all. After surviving a near-fatal battle with Castleman disease, he co-founded the Castleman Disease Collaborative Network (CDCN) to revolutionize research and treatment for this rare condition. Building on that model, he launched Every Cure, a nonprofit initiative that uses AI and data science to uncover new uses for existing drugs and accelerate treatments for countless diseases. His mission is bold but simple: to save lives by changing the way we discover cures.
